| 1. | Study on the protective immunity activated by antigens of adult worms , newborn larvae and muscle larvae of trichinella sprialis
新生幼虫和肌幼虫抗原的保护性免疫研究 |
| 2. | Protective immunity to schistosoma japonicum elicited by co - immunization of cathepsin b dna vaccine with eukaryotic plasmid encoding il
4真核表达质粒联合免疫诱导小鼠保护性的研究 |
| 3. | Construction of attenuated salmonella typhimurium vaccine strain expressing helicobacter pylori catalase and observation on its protective immunity
基因减毒鼠伤寒沙门疫苗菌的构建 |
| 4. | Anti - idiotypic antibody np30 was confirmed with protective immunity of both anti - infection and anti - pathology and may act as a vaccine candidate for schistosomiasis japonica
证南京医科大学博士学位论文明抗独特型抗体np30分子具有较好的抗感染免疫和抗病免疫功效，可作为日本血吸虫病疫苗候选分子。 |
| 5. | Containing many t cell epi - positions and neutralizing antibody epi - positions , the core protein region and envelope protein 2 of hepatitis c virus ( hcv ) structural protein may induce protective immunity responsion in body
丙型肝炎病毒( hepatitiscvirus ， hcv )结构蛋白的核心蛋白( c )和包膜蛋白2 ( e2 )含有多个t细胞表位和中和抗体表位，可诱导机体产生保护性免疫应答。 |
| 6. | Second , ca - np30 conjugate was made by binding ca with np30 . then immunized balb / c mice with ca - np30 , and evaluated its effects on protective immunity , serum specific igg antibody levels and delayed type hypersensitivity ( judged by footpad test )
将钙纳米颗粒ca与np30制备成ca皿30结合物（ ca np30 ） ，主动免疫b从b儿， j 、鼠，观察其对， j 、鼠抗血吸虫感染的保护作用、对血清特异性屹g抗体的影响和足垫反应。 |
| 7. | On these bases , the aim of this study was to develop effective adjuvants for enhancing protective immunity of np30 , we performed a series of researches on nanoparticles , cytokines and traditional chinese medicines , including their effector mechanisms . 1
在此基础上，我们从疫苗佐剂研究入手，分别对纳米颗粒、细胞因子和中药进行系列研究，旨在筛选出能提高np30诱导保护性免疫作用的疫苗佐剂，并对其作用机制进行初步探讨。 |
| 8. | Yherefore , many researchers have shown great concern with the development of vaccines to against schistosomiasis . at early stage , the research of vaccines of schitosomiasis was centered on dead vaccine and athenuated cercaria of schistosomes while molecular vaccine and athenuated cercaria of schistosomes while molecular vaccine is currently the focus of research with anti - infection protective immunity as its main concern . guan xiaohong and zhao weixian ( 1986 ) certified that the allergen of egg granulonma of schistosoma japonicum might firstly come from gut associated antigen ( gaa ) of schistosomula and adult worm and that daa had cross reaction with soluble egg antigen ( sea ) and membrane associated antigen ( maa ) ; and the gaa of schistosoma japonicum might play a sensitizing role in egg granuloma formation
Np30主动免疫c57bl 6对尾蚴攻击感染产生42 . 05的保护力，肝组织减卵率为66 . 63 ； balb c和昆明种小鼠的保护率分别为39 . 53和50 . 46 ；免疫山羊可诱导42 . 78的减虫率，肝组织减卵率为35 . 83 ，粪减卵率为25 ，并可明显抑制肝脏虫卵肉芽肿的大小，肉芽肿数量明显减少，纤维化减轻，体重明显增加，因此np30是南京医科大学博士学位论文很有希望的抗日本血吸虫病疫苗侯选分子。 |
